Manfred Gessler Selected Research

SIOP protocol

8/2012	Treatment-independent miRNA signature in blood of Wilms tumor patients.
2/2007	Loss of 11q and 16q in Wilms tumors is associated with anaplasia, tumor recurrence, and poor prognosis.
6/2006	Target genes of the WNT/beta-catenin pathway in Wilms tumors.

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Manfred Gessler Research Topics

Disease

26	Neoplasms (Cancer) 01/2022 - 03/2005
15	Wilms Tumor (Wilm's Tumor) 10/2021 - 03/2005
2	Breast Neoplasms (Breast Cancer) 01/2020 - 11/2014
2	Carcinogenesis 01/2014 - 03/2005
1	Carcinoma (Carcinomatosis) 01/2020
1	Rhabdoid Tumor (Rhabdoid Tumors) 11/2019
1	Sarcoma (Soft Tissue Sarcoma) 01/2018
1	Prostatic Neoplasms (Prostate Cancer) 05/2014
1	Renal Cell Carcinoma (Grawitz Tumor) 08/2012
1	MASS syndrome 01/2012
1	Neuroblastoma 01/2011
1	Neoplasm Metastasis (Metastasis) 05/2008
1	Pathologic Processes 01/2007
1	Hypoxia (Hypoxemia) 01/2007
1	Cardiomegaly (Heart Hypertrophy) 10/2005
1	Congenital Heart Defects (Congenital Heart Defect) 10/2005
1	Alagille Syndrome (Alagille-Watson Syndrome) 09/2004
1	Cholestasis 09/2004

Drug/Important Bio-Agent (IBA)

5	Biomarkers (Surrogate Marker)IBA 10/2021 - 05/2014
4	MicroRNAs (MicroRNA)IBA 01/2022 - 08/2012
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 08/2012
3	Messenger RNA (mRNA)IBA 01/2020 - 12/2009
3	Transcription Factors (Transcription Factor)IBA 03/2015 - 10/2005
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 05/2008
2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 08/2006
2	RetinoidsIBA 11/2011 - 08/2005
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2011 - 08/2005
2	beta CateninIBA 06/2006 - 03/2005
1	Neutralizing AntibodiesIBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	CytokinesIBA 01/2020
1	Conditioned Culture MediaIBA 01/2020
1	Interleukin-8B ReceptorsIBA 01/2020
1	Monoclonal AntibodiesIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Bevacizumab (Avastin)FDA Link 01/2020
1	ChromatinIBA 01/2019
1	Histones (Histone)IBA 01/2019
1	Mitogen-Activated Protein KinasesIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	Basic Helix-Loop-Helix Transcription FactorsIBA 11/2014
1	fascinIBA 08/2012
1	Ribosomal Proteins (Ribosomal Protein)IBA 08/2012
1	Biological ProductsIBA 11/2011
1	Histone Deacetylase InhibitorsIBA 11/2011
1	FenretinideIBA 11/2011
1	Histone Deacetylases (Histone Deacetylase)IBA 11/2011
1	AntigensIBA 01/2011
1	AutoantibodiesIBA 01/2011
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2010
1	Oxygen (Dioxygen)IBA 01/2007
1	Complementary DNA (cDNA)IBA 06/2006
1	Endothelins (Endothelin)IBA 06/2006
1	Transforming Growth Factor beta (TGF-beta)IBA 08/2005
1	WT1 ProteinsIBA 06/2005
1	LigandsIBA 09/2004

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 10/2021 - 06/2006
6	Therapeutics 01/2020 - 05/2008
3	SIOP protocol 08/2012 - 06/2006
2	Neoadjuvant Therapy 01/2019 - 04/2010
1	Immunotherapy 11/2019
1	Precision Medicine 04/2016
1	Nephrectomy 11/2011
1	Ligation 04/2010